Antiviral Drug Therapy- Exploiting Medicinal Plants

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Antiviral Drug Therapy- Exploiting Medicinal Plants

Abbreviations: CCR: Chemokine Co-receptor; CMV: Cytomegalovirus; CTL: Cytotoxic Lymphocytes; FIPV: Feline Infectious Peritonitis virus; HBV/HCV: Hepatitis B/C Virus; HIV/ AIDS: Human Immunodeficiency Virus/ Acquired Immunodeficiency Syndrome; HSV: Herpes Simplex Virus; JEV: Japanese Encephalitis Virus; MS: Mass Spectrometry; NK: Natural Killer Cells; NMR: Nuclear Magnetic Resonance; NRTI: Nucle...

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Antiviral screening of British Columbian medicinal plants.

One hundred methanolic plant extracts were screened for antiviral activity against seven viruses. Twelve extracts were found to have antiviral activity at the non-cytotoxic concentrations tested. The extracts of Rosa nutkana and Amelanchier alnifolia, both members of the Rosaceae, were very active against an enteric coronavirus. A root extract of another member of the Rosaceae, Potentilla argut...

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Antiviral activity of medicinal plants of Nilgiris.

BACKGROUND & OBJECTIVES Medicinal plants have been traditionally used for different kinds of ailments including infectious diseases. There is an increasing need for substances with antiviral activity since the treatment of viral infections with the available antiviral drugs often leads to the problem of viral resistance. Herpes simplex virus (HSV) causes a variety of life threatening diseases. ...

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Drug discovery from medicinal plants.

Current research in drug discovery from medicinal plants involves a multifaceted approach combining botanical, phytochemical, biological, and molecular techniques. Medicinal plant drug discovery continues to provide new and important leads against various pharmacological targets including cancer, HIV/AIDS, Alzheimer's, malaria, and pain. Several natural product drugs of plant origin have either...

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Exploiting Genetic Interference for Antiviral Therapy

Rapidly evolving viruses are a major threat to human health. Such viruses are often highly pathogenic (e.g., influenza virus, HIV, Ebola virus) and routinely circumvent therapeutic intervention through mutational escape. Error-prone genome replication generates heterogeneous viral populations that rapidly adapt to new selection pressures, leading to resistance that emerges with treatment. Howev...

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ژورنال

عنوان ژورنال: Journal of Antivirals & Antiretrovirals

سال: 2013

ISSN: 1948-5964

DOI: 10.4172/jaa.1000060